This comforting casserole is a perfect blend of shredded cooked chicken, frozen mixed vegetables, and cream of chicken soup, all topped with golden refrigerated biscuits. It's an easy and delicious meal that the whole family will love.
If you don't usually keep frozen mixed vegetables or refrigerated biscuits in your kitchen, you might need to pick these up at the supermarket. The frozen mixed vegetables can be found in the freezer section, while the refrigerated biscuits are typically located near the dairy products.

Ingredients For Chicken And Vegetable Casserole
Shredded cooked chicken: This is the main protein of the dish, providing a hearty and satisfying element.
Frozen mixed vegetables: These add color, texture, and nutrition to the casserole.
Cream of chicken soup: This creates a creamy and flavorful base for the casserole.
Shredded cheddar cheese: Adds a rich, cheesy flavor that complements the other ingredients.
Refrigerated biscuits: These form a golden, flaky topping that contrasts nicely with the creamy filling.
Technique Tip for This Recipe
To ensure the biscuits bake evenly and turn golden brown, consider brushing the tops with a little melted butter before placing them in the oven. This will add a rich flavor and help achieve a beautiful, appetizing color. Additionally, make sure the frozen vegetables are evenly distributed throughout the casserole mixture to ensure every bite is packed with a variety of flavors and textures.
Suggested Side Dishes
Alternative Ingredients
shredded cooked chicken - Substitute with shredded cooked turkey: Turkey provides a similar texture and flavor, making it an excellent alternative.
shredded cooked chicken - Substitute with cooked tofu: For a vegetarian option, tofu offers a protein-rich substitute with a neutral taste that absorbs flavors well.
frozen mixed vegetables - Substitute with fresh mixed vegetables: Fresh vegetables can provide a crisper texture and more vibrant flavor.
frozen mixed vegetables - Substitute with canned mixed vegetables: Canned vegetables are a convenient alternative and are often pre-cooked, reducing preparation time.
cream of chicken soup - Substitute with cream of mushroom soup: This provides a similar creamy consistency with a different but complementary flavor.
cream of chicken soup - Substitute with homemade white sauce: A homemade white sauce made from butter, flour, and milk can replace the soup for a fresher taste and fewer preservatives.
shredded cheddar cheese - Substitute with shredded mozzarella cheese: Mozzarella melts well and offers a mild flavor that complements many dishes.
shredded cheddar cheese - Substitute with shredded Monterey Jack cheese: Monterey Jack has a similar texture and a slightly milder flavor, making it a good alternative.
refrigerated biscuits - Substitute with homemade biscuit dough: Homemade dough can provide a fresher taste and allows for customization of ingredients.
refrigerated biscuits - Substitute with crescent roll dough: Crescent roll dough offers a similar flaky texture and can be used in the same way as biscuits.
Alternative Recipes Similar to This Dish
How to Store or Freeze This Dish
- Allow the casserole to cool completely before storing. This helps prevent condensation, which can make the biscuits soggy.
- Transfer the cooled casserole to an airtight container. If you don't have a container large enough, you can cover the baking dish tightly with aluminum foil or plastic wrap.
- Store the casserole in the refrigerator for up to 3-4 days. Make sure to label it with the date so you know when it was made.
- For longer storage, you can freeze the casserole. Wrap it tightly in plastic wrap, then cover with a layer of aluminum foil. This double layer helps prevent freezer burn.
- When ready to reheat, if frozen, allow the casserole to thaw in the refrigerator overnight. This ensures even reheating.
- Preheat your oven to 350°F (175°C). Remove any plastic wrap and cover the casserole with aluminum foil to prevent the biscuits from burning.
- Bake the casserole for about 20-25 minutes, or until heated through. If the biscuits need more browning, remove the foil for the last 5-10 minutes of baking.
- Alternatively, you can reheat individual portions in the microwave. Place a serving on a microwave-safe plate and cover with a microwave-safe lid or another plate to retain moisture. Heat on medium power for 2-3 minutes, checking and stirring halfway through.
How to Reheat Leftovers
Oven Method:
- Preheat your oven to 350°F (175°C).
- Place the leftover casserole in an oven-safe dish. If it’s already in one, you’re good to go.
- Cover the dish with aluminum foil to prevent the biscuits from drying out.
- Heat for about 20-25 minutes, or until the casserole is heated through and bubbly.
- Remove the foil for the last 5 minutes to let the biscuits crisp up again.
Microwave Method:
- Transfer a portion of the casserole to a microwave-safe dish.
- Cover the dish with a microwave-safe lid or a damp paper towel to retain moisture.
- Heat on medium power for 2-3 minutes. Stir halfway through to ensure even heating.
- Check the temperature and heat in additional 30-second increments if needed until hot.
Stovetop Method:
- Place a portion of the casserole in a non-stick skillet.
- Add a splash of chicken broth or water to prevent sticking and to add moisture.
- Cover the skillet with a lid and heat over medium-low heat.
- Stir occasionally and heat until the casserole is warmed through, about 10-15 minutes.
Air Fryer Method:
- Preheat your air fryer to 350°F (175°C).
- Place a portion of the casserole in the air fryer basket, ensuring the biscuits are on top.
- Heat for 5-7 minutes, checking halfway through to ensure even heating.
- If the biscuits start to brown too quickly, cover them with a small piece of aluminum foil.
Toaster Oven Method:
- Preheat your toaster oven to 350°F (175°C).
- Place the casserole in a toaster oven-safe dish.
- Cover with aluminum foil to keep the biscuits from drying out.
- Heat for 15-20 minutes, removing the foil for the last 5 minutes to crisp up the biscuits.
Slow Cooker Method:
- Transfer the casserole to the slow cooker.
- Set the slow cooker to low heat.
- Cover and heat for 1-2 hours, or until the casserole is thoroughly warmed.
Essential Tools for This Recipe
Oven: Used to bake the casserole at a consistent temperature of 375°F (190°C).
Large bowl: Used to mix together the cooked chicken, frozen vegetables, cream of chicken soup, and shredded cheddar cheese.
Baking dish: Used to hold the casserole mixture and biscuits while baking.
Measuring cups: Used to measure out the shredded cooked chicken, frozen mixed vegetables, and shredded cheddar cheese.
Can opener: Used to open the can of cream of chicken soup.
Mixing spoon: Used to combine all the ingredients in the large bowl.
Oven mitts: Used to safely handle the hot baking dish when removing it from the oven.
How to Save Time on This Recipe
Pre-cook the chicken: Use rotisserie chicken from the store to save time on cooking and shredding.
Use pre-shredded cheese: Buy pre-shredded cheddar cheese to skip the grating step.
Thaw vegetables quickly: Microwave the frozen mixed vegetables for a minute to thaw them faster.
One-bowl mixing: Mix all ingredients in one bowl to minimize cleanup time.
Preheat efficiently: Start preheating the oven while you prepare the ingredients to save time.

Casserole Recipe
Ingredients
Main Ingredients
- 2 cups Cooked Chicken shredded
- 1 cup Frozen Mixed Vegetables
- 1 can Cream of Chicken Soup
- 1 cup Shredded Cheddar Cheese
- 1 package Refrigerated Biscuits
Instructions
- 1. Preheat your oven to 375°F (190°C).
- 2. In a large bowl, mix together the cooked chicken, frozen vegetables, cream of chicken soup, and shredded cheddar cheese.
- 3. Pour the mixture into a baking dish.
- 4. Place the refrigerated biscuits on top of the mixture.
- 5. Bake in the preheated oven for 30-35 minutes, or until the biscuits are golden brown and the casserole is bubbly.
Nutritional Value
Keywords
Suggested Appetizers and Desserts
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